Izvorni kod stranice ATP-zavisna NAD(P)H-hidratna dehidrataza

{{Infobox Enzim
| Name = ATP-zavisna NAD(P)H-hidratna dehidrataza
| EC_number = 4.2.1.93
| CAS_number = 116669-08-0
| IUBMB_EC_number = 4/2/1/93
| GO_code = 
| image = 
| width = 
| caption =
}}
'''ATP-zavisna NAD(P)H-hidratna dehidrataza''' ({{EC broj|4.2.1.93}}, ''redukovani nikotinamid adenin dinukleotid hidratna dehidrataza'', ''ATP-zavisna H4NAD(P)<sup>+</sup>OH dehidrataza'', ''(6S)-beta-6-hidroksi-1,4,5,6-tetrahidronikotinamid-adenin-dinukleotid hidrolijaza (ATP-hidroliza)'', ''(6S)-6-beta-hidroksi-1,4,5,6-tetrahidronikotinamid-adenin-dinukleotid hidrolijaza (ATP hidroliza'', ''formira NADH)'') je [[enzim]] sa sistematskim imenom ''(6S)-6beta-hidroksi-1,4,5,6-tetrahidronikotinamid-adenin-dinukleotid hidrolijaza (ATP-hidroliza, formira NADH)''.<ref>{{cite journal | title = Enzymatic conversion of a reduced diphosphopyridine nucleotide derivative to reduced diphosphopyridine nucleotide |author = Meinhart, J.O., Chaykin, S. and Krebs, E.G. |journal = J. Biol. Chem. |date = 1956 |volume = 220 |pages = 821-829 |pmid = 13331940}}</ref><ref>{{cite journal | title = Synthesis and degradation of monohydroxytetrahydronicotinamide adenine dinucleotide phosphate |author = Regueiro Varela, B., Amelunxen, R. and Grisolia, S. |journal = Physiol. Chem. Phys. |date = 1970 |volume = 2 |pages = 445-454 |pmid = }}</ref><ref>{{cite journal | title = Equilibrium of 5,6-hydration of NADH and mechanism of ATP-dependent dehydration |author = Acheson, S.A., Kirkman, H.N. and Wolfenden, R. |journal = Biochemistry |date = 1988 |volume = 27 |pages = 7371-7375 |pmid = 3061454}}</ref><ref>{{cite journal | title = Extremely conserved ATP- or ADP-dependent enzymatic system for nicotinamide nucleotide repair |author = Marbaix, A.Y., Noel, G., Detroux, A.M., Vertommen, D., Van Schaftingen, E. and Linster, C.L. |journal = J. Biol. Chem. |date = 2011 |volume = 286 |pages = 41246-41252 |pmid = 21994945}}</ref> Ovaj enzim [[Kataliza|katalizuje]] sledeću [[hemijska reakcija|hemijsku reakciju]]

: (1) [[Adenozin-trifosfat|ATP]] + (6S)-6beta-hidroksi-1,4,5,6-tetrahidronikotinamid-adenin dinukleotid <math>\rightleftharpoons</math> [[Adenozin-difosfat|ADP]] + [[fosfat]] + NADH
: (2) [[Adenozin-trifosfat|ATP]] + (6S)-6beta-hidroksi-1,4,5,6-tetrahidronikotinamid-adenin dinukleotid fosfat <math>\rightleftharpoons</math> [[Adenozin-difosfat|ADP]] + fosfat + NADPH

Ovaj enzim deluje jednakom brzinom na hidratisani NADH i hidratisani NADPH.

== Reference ==
{{reflist}}

== Literatura ==
{{refbegin|2}}
* {{PriceEnzymology3rd}}
* {{TooneAdvancesInEnzymology}}
* {{Branden ProteinStructure2nd}}
* {{SegelEnzymeKinetics}}
* {{CopelandEvaluationOfEnzymeInhibitors2nd}}
* {{MichalBiochemicalPathways}}
{{refend}}

== Vanjske veze ==
* {{MeshName|ATP-dependent+NAD(P)H-hydrate+dehydratase}}

{{Enzimi}}

[[Kategorija:EC 4.2.1]]