Izvorni kod stranice Beta-ketoacil-(acil-nosilac-protein) sintaza III

{{Infobox Enzim
| Name = Beta-ketoacil-(acil-nosilac-protein) sintaza III
| EC_number = 2.3.1.180
| CAS_number = 1048646-78-1
| IUBMB_EC_number = 2/3/1/180
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Beta-ketoacil-(acil-nosilac-protein) sintaza III''' ({{EC broj|2.3.1.180}}, ''3-oksoacil:ACP sintaza III'', ''3-ketoacil-acil nosilac protein sintaza III'', ''KASIII'', ''KAS III'', ''FabH'', ''beta-ketoacil-acil nosilac protein sintaza III'', ''beta-ketoacil-ACP sintaza III'', ''beta-ketoacil (acil nosilac protein) sintaza III'', ''acetil-KoA:malonil-(acil-nosilac-protein) C-aciltransferaza'') je [[enzim]] sa sistematskim imenom ''acetil-KoA:malonil-(acil-nosilac protein) C-aciltransferaza''.<ref>{{cite journal | title = Isolation and characterization of the &beta;-ketoacyl-acyl carrier protein synthase III gene (''fabH'') from ''Escherichia coli'' K-12 |author = Tsay, J.T., Oh, W., Larson, T.J., Jackowski, S. and Rock, C.O. |journal = J. Biol. Chem. |date = 1992 |volume = 267 |pages = 6807-6814 |pmid = 1551888}}</ref><ref>{{cite journal | title = Characterization of &beta;-ketoacyl-acyl carrier protein synthase III from ''Streptomyces glaucescens'' and its role in initiation of fatty acid biosynthesis | url = https://archive.org/details/sim_journal-of-bacteriology_1998-09_180_17/page/4481 |author = Han, L., Lobo, S. and Reynolds, K.A. |journal = J. Bacteriol. |date = 1998 |volume = 180 |pages = 4481-4486 |pmid = 9721286}}</ref><ref>{{cite journal | title = Identification, substrate specificity, and inhibition of the ''Streptococcus pneumoniae'' &beta;-ketoacyl-acyl carrier protein synthase III (FabH) |author = Khandekar, S.S., Gentry, D.R., Van Aller, G.S., Warren, P., Xiang, H., Silverman, C., Doyle, M.L., Chambers, P.A., Konstantinidis, A.K., Brandt, M., Daines, R.A. and Lonsdale, J.T. |journal = J. Biol. Chem. |date = 2001 |volume = 276 |pages = 30024-30030 |pmid = 11375394}}</ref><ref>{{cite journal | title = Identification and substrate specificity of &beta;-ketoacyl (acyl carrier protein) synthase III (mtFabH) from ''Mycobacterium tuberculosis'' |author = Choi, K.H., Kremer, L., Besra, G.S. and Rock, C.O. |journal = J. Biol. Chem. |date = 2000 |volume = 275 |pages = 28201-28207 |pmid = 10840036}}</ref><ref>{{cite journal | title = Crystal structure and substrate specificity of the &beta;-ketoacyl-acyl carrier protein synthase III (FabH) from ''Staphylococcus aureus'' |author = Qiu, X., Choudhry, A.E., Janson, C.A., Grooms, M., Daines, R.A., Lonsdale, J.T. and Khandekar, S.S. |journal = Protein Sci. |date = 2005 |volume = 14 |pages = 2087-2094 |pmid = 15987898}}</ref><ref>{{cite journal | title = Alteration of the fatty acid profile of ''Streptomyces coelicolor'' by replacement of the initiation enzyme 3-ketoacyl acyl carrier protein  synthase III (FabH) | url = https://archive.org/details/sim_journal-of-bacteriology_2005-06_187_11/page/3795 |author = Li, Y., Florova, G. and Reynolds, K.A. |journal = J. Bacteriol. |date = 2005 |volume = 187 |pages = 3795-3799 |pmid = 15901703}}</ref><ref>{{Cite book | chapter = Biosynthesis of membrane lipids | title = Escherichia coli and Salmonella: Cellular and Molecular Biology |author = Cronan, J.E., Jr. and Rock, C.O. |date = 1996 |volume = 1 |pages = 612-636 |editor = Neidhardt, F.C. |edition  = 2nd |publisher = ASM Press |location = Washington, DC }}</ref> Ovaj enzim [[Kataliza|katalizuje]] sledeću [[hemijska reakcija|hemijsku reakciju]]

: acetil-KoA + malonil-[acil-nosilac protein] <math>\rightleftharpoons</math> acetoacetil-[acil-nosilac protein] + KoA + CO<sub>2</sub>

Ovaj enzim učestvuje u sistemu biosinteze disociranih masnih kiselina kod biljki i bakterija.

== Reference ==
{{reflist}}

== Literatura ==
{{refbegin|2}}
* {{PriceEnzymology3rd}}
* {{TooneAdvancesInEnzymology}}
* {{Branden ProteinStructure2nd}}
* {{SegelEnzymeKinetics}}
* {{CopelandEvaluationOfEnzymeInhibitors2nd}}
* {{MichalBiochemicalPathways}}
{{refend}}
* {{Cite book |ref= harv|chapter = Biosynthesis of membrane lipids | title = Escherichia coli and Salmonella: Cellular and Molecular Biology |author = Cronan, J.E., Jr. and Rock, C.O. |date = 1996 |volume = 1 |pages = 612-636 |editor = Neidhardt, F.C. |edition  = 2nd |publisher = ASM Press |location = Washington, DC }}

== Vanjske veze ==
* {{MeshName|Beta-ketoacyl-(acyl-carrier-protein)+synthase+III}}

{{Enzimi}}

[[Kategorija:EC 2.3.1]]