Izvorni kod stranice Glutaril-7-aminocefalosporansko-kiselinska acilaza

{{Infobox Enzim
| Name = Glutaril-7-aminocefalosporansko-kiselinska acilaza
| EC_number = 3.5.1.93
| CAS_number = 56645-46-6
| IUBMB_EC_number = 3/5/1/93
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Glutaril-7-aminocefalosporansko-kiselinska acilaza''' ({{EC broj|3.5.1.93}}, ''7beta-(4-karboksibutanamido)cefalosporansko kiselinska acilaza'', ''cefalosporin C acilaza'', ''glutaril-7-ACA acilaza'', ''CA'', ''GCA'', ''GA'', ''cefalosporinska acilaza'', ''glutaril-7-aminocefalosporanska kiselinskaa acilaza'', ''GL-7-ACA acilaza'') je [[enzim]] sa sistematskim imenom ''(7R)-7-(4-karboksibutanamido)cefalosporanat amidohidrolaza''.<ref>{{cite journal | title = High-level production, chemical modification and site-directed mutagenesis of a cephalosporin C acylase from ''Pseudomonas'' strain N176 |author = Ishii, Y., Saito, Y., Fujimura, T., Sasaki, H., Noguchi, Y., Yamada, H., Niwa, M. and Shimomura, K. |journal = Eur. J. Biochem. |date = 1995 |volume = 230 |pages = 773-778 |pmid = 7607251}}</ref><ref>{{cite journal | title = Crystallization and preliminary X-ray analysis of cephalosporin C acylase from ''Pseudomonas'' sp. strain N176 |author = Kinoshita, T., Tada, T., Saito, Y., Ishii, Y., Sato, A. and Murata, M. |journal = Acta Crystallogr. D Biol. Crystallogr. |date = 2000 |volume = 56 |pages = 458-459 |pmid = 10739919}}</ref><ref>{{cite journal | title = Characterization of an industrial biocatalyst: immobilized glutaryl-7-ACA acylase | url = https://archive.org/details/sim_biotechnology-and-bioengineering_2000-10-20_70_2/page/n130 |author = Monti, D., Carrea, G., Riva, S., Baldaro, E. and Frare, G. |journal = Biotechnol. Bioeng. |date = 2000 |volume = 70 |pages = 239-244 |pmid = 10972935}}</ref><ref>{{cite journal | title = Crystallization and preliminary X-Ray diffraction analysis of glutaryl-7-aminocephalosporanic acid acylase from ''Pseudomonas'' sp. GK16 |author = Kwon, T.H., Rhee, S., Lee, Y.S., Park, S.S. and Kim, K.H. |journal = J. Struct. Biol. |date = 2000 |volume = 131 |pages = 79-81 |pmid = 10945972}}</ref><ref>{{cite journal | title = The 2.0 &Aring; crystal structure of cephalosporin acylase |author = Kim, Y., Yoon, K.-H., Khang, Y., Turley, S. and Hol, W.G.J. |journal = Structure |date = 2000 |volume = 8 |pages = 1059-1068 |pmid = 11080627}}</ref><ref>{{cite journal | title = Affinity alkylation of the Trp-B4 residue of the &beta;-subunit of the glutaryl 7-aminocephalosporanic acid acylase of ''Pseudomonas'' sp. 130 |author = Huang, X., Zeng, R., Ding, X., Mao, X., Ding, Y., Rao, Z., Xie, Y., Jiang, W. and Zhao, G. |journal = J. Biol. Chem. |date = 2002 |volume = 277 |pages = 10256-10264 |pmid = 11782466}}</ref><ref>{{cite journal | title = Crystal structures of glutaryl 7-aminocephalosporanic acid acylase: insight into autoproteolytic activation |author = Kim, J.K., Yang, I.S., Rhee, S., Dauter, Z., Lee, Y.S., Park, S.S. and Kim, K.H. |journal = Biochemistry |date = 2003 |volume = 42 |pages = 4084-4093 |pmid = 12680762}}</ref> Ovaj enzim [[Kataliza|katalizuje]] sledeću [[hemijska reakcija|hemijsku reakciju]]

: (7R)-7-(4-karboksibutanamido)cefalosporanat + H<sub>2</sub>O <math>\rightleftharpoons</math> (7R)-7-aminocefalosporanat + [[glutarat]]

Ovaj enzim formira 7-aminocefalosporansku kiselinu.

== Reference ==
{{reflist}}

== Literatura ==
{{refbegin|2}}
* {{PriceEnzymology3rd}}
* {{TooneAdvancesInEnzymology}}
* {{Branden ProteinStructure2nd}}
* {{SegelEnzymeKinetics}}
* {{CopelandEvaluationOfEnzymeInhibitors2nd}}
* {{MichalBiochemicalPathways}}
{{refend}}

== Vanjske veze ==
* {{MeshName|Glutaryl-7-aminocephalosporanic-acid+acylase}}

{{Enzimi}}

[[Kategorija:EC 3.5.1]]