Izvorni kod stranice Koenzim F420-1:gama-L-glutamat ligaza

{{Infobox Enzim
| Name = Koenzim F420-1:gama-L-glutamat ligaza
| EC_number = 6.3.2.34
| CAS_number = 
| IUBMB_EC_number = 6/3/2/34
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Koenzim F420-1:gama-L-glutamat ligaza''' ({{EC broj|6.3.2.34}}, ''F420:gama-glutamil ligaza'', ''CofE-AF'', ''MJ0768'', ''CofE'') je [[enzim]] sa sistematskim imenom ''L-glutamat:koenzim F420-1 ligaza (formira GDP)''.<ref>{{cite journal | title = CofE catalyzes the addition of two glutamates to F<sub>420</sub>-0 in F<sub>420</sub> coenzyme biosynthesis in ''Methanococcus jannaschii'' |author = Li, H., Graupner, M., Xu, H. and White, R.H. |journal = Biochemistry |date = 2003 |volume = 42 |pages = 9771-9778 |pmid = 12911320}}</ref><ref>{{cite journal | title = Structure of an amide bond forming F<sub>420</sub>:&gamma;-glutamyl ligase from ''Archaeoglobus fulgidus'' – a member of a new family of non-ribosomal  peptide synthases |author = Nocek, B., Evdokimova, E., Proudfoot, M., Kudritska, M., Grochowski, L.L., White, R.H., Savchenko, A., Yakunin, A.F., Edwards, A. and Joachimiak, A. |journal = J. Mol. Biol. |date = 2007 |volume = 372 |pages = 456-469 |pmid = 17669425}}</ref> Ovaj enzim [[Kataliza|katalizuje]] sledeću [[hemijska reakcija|hemijsku reakciju]]

: GTP + koenzim F420-1 + L-[[glutamat]] <math>\rightleftharpoons</math> GDP + [[fosfat]] + koenzim gama-F420-2

Ovaj protein katalizuje the sukcesivnu adiciju dva glutamatna ostatka na kofaktor F420 putem dve nezavisne reakcije.

== Reference ==
{{reflist}}

== Literatura ==
{{refbegin|2}}
* {{PriceEnzymology3rd}}
* {{TooneAdvancesInEnzymology}}
* {{Branden ProteinStructure2nd}}
* {{SegelEnzymeKinetics}}
* {{CopelandEvaluationOfEnzymeInhibitors2nd}}
* {{MichalBiochemicalPathways}}
{{refend}}

== Vanjske veze ==
* {{MeshName|Coenzyme+F420-1:gamma-L-glutamate+ligase}}

{{Enzimi}}

[[Kategorija:EC 6.3.2]]