Izvorni kod stranice Pimelil-(acil-nosilac protein) metil estarska esteraza

{{Infobox Enzim
| Name = Pimelil-(acil-nosilac protein) metil estarska esteraza
| EC_number = 3.1.1.85
| CAS_number = 
| IUBMB_EC_number = 3/1/1/85
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Pimelil-(acil-nosilac protein) metil estarska esteraza''' ({{EC broj|3.1.1.85}}, ''BioH'') je [[enzim]] sa sistematskim imenom ''pimelil-(acil-nosilac protein) metil estar hidrolaza''.<ref>{{cite journal | title = Integrating structure, bioinformatics, and enzymology to discover function: BioH, a new carboxylesterase from ''Escherichia coli'' |author = Sanishvili, R., Yakunin, A.F., Laskowski, R.A., Skarina, T., Evdokimova, E., Doherty-Kirby, A., Lajoie, G.A., Thornton, J.M., Arrowsmith, C.H., Savchenko, A., Joachimiak, A. and Edwards, A.M. |journal = J. Biol. Chem. |date = 2003 |volume = 278 |pages = 26039-26045 |pmid = 12732651}}</ref><ref>{{cite journal | title = To be free or not: the fate of pimelate in ''Bacillus sphaericus'' and in ''Escherichia coli'' | url = https://archive.org/details/sim_molecular-microbiology_1996-02_19_3/page/645 |author = Lemoine, Y., Wach, A. and Jeltsch, J.M. |journal = Mol. Microbiol. |date = 1996 |volume = 19 |pages = 645-647 |pmid = 8830257}}</ref><ref>{{cite journal | title = Purification and characterisation of the BIOH protein from the biotin biosynthetic pathway |author = Tomczyk, N.H., Nettleship, J.E., Baxter, R.L., Crichton, H.J., Webster, S.P. and Campopiano, D.J. |journal = FEBS Lett. |date = 2002 |volume = 513 |pages = 299-304 |pmid = 11904168}}</ref><ref>{{cite journal | title = Biotin synthesis begins by hijacking the fatty acid synthetic pathway |author = Lin, S., Hanson, R.E. and Cronan, J.E. |journal = Nat. Chem. Biol. |date = 2010 |volume =  |pages = - |pmid = 20693992}}</ref> Ovaj enzim [[Kataliza|katalizuje]] sledeću [[hemijska reakcija|hemijsku reakciju]]

: pimelil-[acil-nosilac protein] metil estar + H<sub>2</sub>O <math>\rightleftharpoons</math> pimelil-[acil-nosilac protein] + [[metanol]]

Ovaj enzim učestvuje u biosintezi [[biotin]]a u Gram-negativim bakterijama.

== Reference ==
{{reflist}}

== Literatura ==
{{refbegin|2}}
* {{PriceEnzymology3rd}}
* {{TooneAdvancesInEnzymology}}
* {{Branden ProteinStructure2nd}}
* {{SegelEnzymeKinetics}}
* {{CopelandEvaluationOfEnzymeInhibitors2nd}}
* {{MichalBiochemicalPathways}}
{{refend}}

== Vanjske veze ==
* {{MeshName|Pimelyl-(acyl-carrier+protein)+methyl+ester+esterase}}

{{Enzimi}}

[[Kategorija:EC 3.1.1]]