Izvorni kod stranice Sepiapterin reduktaza (formira L-treo-7,8-dihidrobiopterin)

{{Infobox Enzim
| Name = Sepiapterin reduktaza (formira L-treo-7,8-dihidrobiopterin)
| EC_number = 1.1.1.325
| CAS_number = 9059-48-7
| IUBMB_EC_number = 1/1/1/325
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Sepiapterin reduktaza (formira L-treo-7,8-dihidrobiopterin)''' ({{EC broj|1.1.1.325}}, ''sepiapterinska reduktaza'') je [[enzim]] sa sistematskim imenom ''L-treo-7,8-dihidrobiopterin:NADP<sup>+</sup> oksidoreduktaza''.<ref>{{cite journal | title = Sepiapterin reductase producing L-''threo''-dihydrobiopterin from ''Chlorobium tepidum'' | url = https://archive.org/details/sim_biochemical-journal_1999-06-01_340/page/n154 |author = Cho, S.H., Na, J.U., Youn, H., Hwang, C.S., Lee, C.H. and Kang, S.O. |journal = Biochem. J. |date = 1999 |volume = 340 |pages = 497-503 |pmid = 10333495}}</ref><ref>{{cite journal | title = Expression, purification, crystallization and preliminary X-ray analysis of sepiapterin reductase from ''Chlorobium tepidum'' |author = Supangat, S., Choi, Y.K., Park, Y.S., Son, D., Han, C.D. and Lee, K.H. |journal = Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. |date = 2005 |volume = 61 |pages = 202-204 |pmid = 16510994}}</ref> Ovaj enzim [[Kataliza|katalizuje]] sledeću [[hemijska reakcija|hemijsku reakciju]]

: (1) L-treo-7,8-dihidrobiopterin + NADP<sup>+</sup> <math>\rightleftharpoons</math> sepiapterin + NADPH + H<sup>+</sup>
: (2) L-treo-tetrahidrobiopterin + 2 NADP<sup>+</sup> <math>\rightleftharpoons</math> 6-piruvoil-5,6,7,8-tetrahidropterin + 2 NADPH + 2 H<sup>+</sup>

Ovaj enzim izolovan iz bakterije ''Hlorobium tepidum'' katalizuje finalni korak [[de novo sinteza|de novo sinteze]] tetrahidrobiopterina iz GTP-a, cf. [[EC 1.1.1.153]], sepiapterinska reduktaza (formira L-eritro-7,8-dihidrobiopterin).

== Reference ==
{{reflist}}

== Literatura ==
{{refbegin|2}}
* {{PriceEnzymology3rd}}
* {{TooneAdvancesInEnzymology}}
* {{Branden ProteinStructure2nd}}
* {{SegelEnzymeKinetics}}
* {{CopelandEvaluationOfEnzymeInhibitors2nd}}
* {{MichalBiochemicalPathways}}
{{refend}}

== Vanjske veze ==
* {{MeshName|Sepiapterin+reductase+(L-threo-7,8-dihydrobiopterin+forming)}}

{{Enzimi}}

[[Kategorija:EC 1.1.1]]