Izvorni kod stranice Delta12-masna-kiselina desaturaza

{{Infobox Enzim
| Name = Delta12-masna-kiselina desaturaza
| EC_number = 1.14.19.6
| CAS_number = 
| IUBMB_EC_number = 1/14/19/6
| GO_code = 
| image = 
| width = 
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}}
'''Delta12-masna-kiselina desaturaza''' ({{EC broj|1.14.19.6}}, ''Delta12 masno kiselinska desaturaza'', ''Delta12(omega6)-desaturaza'', ''oleoil-KoA Delta12 desaturaza'', ''Delta12 desaturaza'', ''Delta12-desaturaza'') je [[enzim]] sa sistematskim imenom ''acil-KoA,vodonik donor:kiseonik Delta12-oksidoreduktaza''.<ref>{{cite journal | title = Characterization of the &Delta;<sup>12</sup> desaturase in the American cockroach, ''Periplaneta americana'': the nature of the substrate |author = Borgeson, C.E., de Renobales, M. and Blomquist, G.J. |journal = Biochim. Biophys. Acta |date = 1990 |volume = 1047 |pages = 135-140 |pmid = 2248971}}</ref><ref>{{cite journal | title = Biosynthetic pathway for producing the sex pheromone component (''Z'',''E'')-9,12-tetradecadienyl acetate in moths involves a &Delta;<sup>12</sup>  desaturase | url = https://archive.org/details/sim_cellular-and-molecular-life-sciences_1997-06_53_6/page/501 |author = Jurenka, R.A. |journal = Cell. Mol. Life Sci. |date = 1997 |volume = 53 |pages = 501-505 |pmid = 9230926}}</ref><ref>{{cite journal | title = Study of the &Delta;<sup>12</sup>-desaturase system of ''Lipomyces starkeyi'' | url = https://archive.org/details/sim_lipids_1996-03_31_3/page/253 |author = Lomascolo, A., Dubreucq, E. and Galzy, P. |journal = Lipids |date = 1996 |volume = 31 |pages = 253-259 |pmid = 8900454}}</ref><ref>{{cite journal | title = Recent advances in the biochemistry and molecular biology of fatty acyl desaturases | url = https://archive.org/details/sim_progress-in-lipid-research_1998-05_37_1_0/page/n76 |author = Tocher, D.R., Leaver, M.J. and Hodgson, P.A. |journal = Prog. Lipid Res. |date = 1998 |volume = 37 |pages = 73-117 |pmid = 9829122}}</ref> Ovaj enzim [[Kataliza|katalizuje]] sledeću [[hemijska reakcija|hemijsku reakciju]]:

: acil-KoA + redukovani akceptor + O<sub>2</sub> <math>\rightleftharpoons</math> Delta12-acil-KoA + akceptor + 2H<sub>2</sub>O

U kvascu ''[[Lipomyces starkeyi]]'' i američkoj bubašvabi, ovaj mikrozomalni enzim konvertuje oleoil-KoA u linoleoil-KoA. Kod moljaca ''[[Cadra cautella]]'' i ''[[Spodoptera]]'', on konvertuje (Z)-tetradek-9-enoinsku kiselinu (9Z,12E)-tetradeka-9,12-dienoinsku kiselinu, koja se redukuje i acetiluje čime se formira acetatni estar [[feromon]]a.

== Reference ==
{{reflist}}

== Literatura ==
{{refbegin|2}}
* {{PriceEnzymology3rd}}
* {{TooneAdvancesInEnzymology}}
* {{Branden ProteinStructure2nd}}
* {{SegelEnzymeKinetics}}
* {{CopelandEvaluationOfEnzymeInhibitors2nd}}
* {{MichalBiochemicalPathways}}
{{refend}}

== Vanjske veze ==
* {{MeshName|Delta12-fatty-acid+desaturase}}

{{Enzimi}}

[[Kategorija:EC 1.14.19]]